Multimodal imaging including swept source optical coherence tomography angiography in a case with sclerochoroidal calcification

TETİK D., GÜNDÜZ A. K.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, vol.40, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 40
  • Publication Date: 2022
  • Doi Number: 10.1016/j.pdpdt.2022.103054
  • Journal Name: PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Keywords: Fundus autofluorescence, Optical coherence tomography, Optical coherence tomography angiography, Sclerochoroidal calcification, Fluorescein angiography, Ultrasonography, NEOVASCULARIZATION
  • Ankara University Affiliated: Yes

Abstract

Purpose: We report a case of idiopathic sclerochoroidal calcification (SCC) evaluated with multimodal imaging including swept source optical coherence tomography angiography (SS-OCTA).Case presentation: A 52-year-old man was diagnosed with sclerochoroidal calcification in the left eye. Multimodal imaging revealed mixed hypoautofluorescence and hyperautofluorescence on fundus autofluorescence (FAF) imaging; an acoustically solid lesion with hyperreflective deposits on ultrasonography (USG); a rocky configu-ration with marked disruption of outer retinal layers and abrupt transition from normal to tumor tissue on swept source optical coherence tomography (SS-OCT); hyporeflective plexus in the outer retinal and choroidal slabs and a retinochoroidal shunt vessel on SS-OCTA; and central hypofluorescence with intervening patchy hyper -fluorescent areas, diffuse peripheral window defects, and a retinochoroidal shunt vessel on fluorescein angiog-raphy (FA). Systemic evaluation including serum parathyroid hormone, calcium, phosphorus, albumin levels, and urine analysis were normal.Conclusion: Sclerochoroidal calcification is a rare ocular tumor that may be idiopathic or secondary to several nephrological or endocrinological diseases involving calcium and phosphorus mechanism. Multimodal imaging with FAF, USG, OCT, OCTA, and FA help to identify the distinguishing features of the tumor and differentiate it from other entities.