Akademik Veri Yönetim Sistemi
Drug Development and Industrial Pharmacy, cilt.20, sa.14, ss.2323-2331, 1994 (SCI-Expanded)
In the manufacturing of tablets, direct tableting agents are not only used in direct compression, but are also used in wet granulation and slugging methods. These agents are effective only if their particle size and form is appropriate. However, the precompression, milling and grinding which are applied in the slugging method changes the particular properties of these agents. In this study, microcrystalline cellulose tablets were prepared both by direct compression and slugging. The consolidation, compressibility and flow properties of the two mixed powders were compared. Finally, it was observed that the compressibility of the mixed powder was influenced negatively by the slugging method. © 1994 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.