Optic Nerve Head Microvascular Changes Associated with Intracranial Aneurysms
Beyoglu Eye Journal, cilt.10, sa.2, ss.101-106, 2025 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 10 Sayı: 2
- Basım Tarihi: 2025
- Doi Numarası: 10.14744/bej.2025.98698
- Dergi Adı: Beyoglu Eye Journal
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.101-106
- Anahtar Kelimeler: Intracranial aneurysm, microvascular indices, optic coherence tomography angiography, optic nerve head, subarachnoid hemorrhage
- Ankara Üniversitesi Adresli: Evet
Özet
Objectives: The aim of our study is to report optic nerve head (ONH) microvascular changes secondary to intracranial saccular aneurysms, evaluated by optic coherence tomography angiography. Methods: A prospective study was conducted on consecutive intracranial saccular aneurysm patients who underwent neurosurgical intervention and consulted for ophthalmic evaluation at the post-operative period. Comprehensive ophthalmic evaluation, including best-corrected visual acuity, manifest refraction, color vision, pupillary light reflexes, intraocular pressure, slit-lamp biomicroscopy, fundoscopy, and investigation of the function of cranial nerves, was performed. Demographical and clinical data of eyes with intracranial aneurysm (Group 1) were compared to those of age-matched controls (Group 2). In patients with unilateral intracranial aneurysm, microvascular indices of the ipsilateral eye were also compared with those of the contralateral eye. Results: Twenty-eight eyes of 16 patients in Group 1 and 32 eyes of 16 age-matched healthy controls in Group 2 were included in the study. In Group 1, only 1 patient was diagnosed incidentally, whereas the remaining 15 patients were diagnosed after subarachnoid hemorrhage (SAH). ONH microvascular indices were similar in both groups (p>0.05). Both vascular density and thickness were decreased at the nasal inferior sector of ONH in Group 1, compared to Group 2; however, these differences were statistically insignificant. In Group 1, 8 patients have unilateral intracranial aneurysm. Microvascular indices at the ipsilateral eye were statistically insignificantly increased compared to those at the contralateral eye of patients with unilateral intracranial aneurysm. Conclusion: Intracranial saccular aneurysms, associated SAH, or neurosurgical intervention did not seem to cause any significant change in ONH microvascular indices. Further studies with a larger sample size and evaluating intracranial aneurysms located in different anatomical regions will contribute to the interpretation of the present results.