SURVEY OF OPHTHALMOLOGY, vol.43, no.6, pp.551-555, 1999 (SCI-Expanded)
A 57-year-old man with non-Hodgkin's B-cell lymphoma of the abdominal lymph nodes developed moderate cells in thr anterior chamber and vitreous, choroidal infiltration, and total non-rhegmatogenous retinal detachment in both eyes while receiving chemotherapy. After a diagnostic vitrectomy in the left eye was nonrevealing, the patient was referred to the oncology service. Fine-needle aspiration biopsy of the choroidal infiltrate was not done because of poor visualization of the choroid through the turbid subretinal fluid. Transscleral choroidal biopsy was performed without complications and disclosed diffuse high-grade B-cell lymphoma and no signs of endogenous infection. Transscleral choroidal biopsy is a useful technique in eyes with choroidal infiltration, especially when hazy media prohibit fine needle biopsy. (Surv Ophthalmol 43:551-555, 1999. (C) 1999 by Elsevier Science Inc. All rights reserved.).