TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.33, sa.3, ss.122-125, 2008 (SCI-Expanded, TRDizin)
Experimental data suggest that resveratrol, an antioxidant molecule, has beneficial effects on cardiovascular system. Evidence-based medicine (EBM) aims to apply evidence gained from the hard end-point placebo controlled randomized clinical trials to certain parts of medical practice. There have been many molecules, including vitamin E, which were shown to have positive effects in experimental models (that is further supported by observational clinical studies) but failed to show any benefit in hard end-point randomized clinical trials.