Efficiency of L-arginine enriched cardioplegia and non-cardioplegic reperfusion in ischemic hearts

Kiziltepe, U; Tunctan, B; Eyileten, ZB; Sirlak, MUSTAFA; Arikbuku, M; Tasoz, R; Uysalel, A; Ozyurda, U

doi:10.1016/j.ijcard.2003.08.015

Efficiency of L-arginine enriched cardioplegia and non-cardioplegic reperfusion in ischemic hearts

Kiziltepe U., Tunctan B., Eyileten Z., Sirlak M., Arikbuku M., Tasoz R., ...Daha Fazla

INTERNATIONAL JOURNAL OF CARDIOLOGY, cilt.97, sa.1, ss.93-100, 2004 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 97 Sayı: 1
Basım Tarihi: 2004
Doi Numarası: 10.1016/j.ijcard.2003.08.015
Dergi Adı: INTERNATIONAL JOURNAL OF CARDIOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.93-100
Anahtar Kelimeler: nitric oxide, coronary artery bypass surgery, ischemia/reperfusion, cardioplegia, NITRIC-OXIDE, MYOCARDIAL-ISCHEMIA, PROTECTION, PEROXYNITRITE, INJURY, ARREST
Ankara Üniversitesi Adresli: Evet

Özet

Objective: Endothelial dysfunction with decreased nitric oxide (NO) levels has been implicated on reperfusion injury. Although L-arginine has been shown to diminish reperfusion injury in in vitro studies, clinical studies were very limited.