The Inflammation Network in the Pathogenesis of Erectile Dysfunction: Attractive Potential Therapeutic Targets

KAYA SEZGİNER E., GÜR S.

CURRENT PHARMACEUTICAL DESIGN, cilt.26, sa.32, ss.3955-3972, 2020 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 26 Sayı: 32
  • Basım Tarihi: 2020
  • Doi Numarası: 10.2174/1381612826666200424161018
  • Dergi Adı: CURRENT PHARMACEUTICAL DESIGN
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.3955-3972
  • Anahtar Kelimeler: Erectile dysfunction, endothelial dysfunction, metabolic disease, inflammation, cytokines, anti-inflammatory drugs, NITRIC-OXIDE SYNTHASE, NECROSIS-FACTOR-ALPHA, ENDOTHELIUM-DEPENDENT VASODILATATION, CARDIOVASCULAR RISK-FACTORS, RENIN-ANGIOTENSIN SYSTEM, CORONARY-ARTERY-DISEASE, CAVERNOUS NERVE INJURY, C-REACTIVE PROTEIN, TNF-ALPHA, METABOLIC SYNDROME
  • Ankara Üniversitesi Adresli: Evet

Özet

Background: Erectile dysfunction (ED) is an evolving health problem in the aging male population. Chronic low-grade inflammation is a critical component of ED pathogenesis and a probable intermediate stage of endothelial dysfunction, especially in metabolic diseases, with the inclusion of obesity, metabolic syndrome. and diabetes.