A Study on Classification and Performance Evaluation in Logistic Regression Analysis


Eviren E. N., Atakan C.

A Study on Classification and Performance Evaluation in Logistic Regression Analysis, Yalçın Tahtalı,Lütfi Bayyurt,Samet Hasan Abacı, Editör, Ozgur Press , Gaziantep, ss.121-138, 2026

  • Yayın Türü: Kitapta Bölüm / Araştırma Kitabı
  • Basım Tarihi: 2026
  • Doi Numarası: 10.58830/ozgur.pub1404.c5659
  • Yayınevi: Ozgur Press
  • Basıldığı Şehir: Gaziantep
  • Sayfa Sayıları: ss.121-138
  • Editörler: Yalçın Tahtalı,Lütfi Bayyurt,Samet Hasan Abacı, Editör
  • Ankara Üniversitesi Adresli: Evet

Özet

Logistic regression is a widely used statistical method for binary classification problems. This study evaluates variable selection, multicollinearity management, parameter estimation, and classification performance of the logistic regression model for binary classification. The dataset consists of 5880 synthetic observations (4000 normal, 1880 anomaly) generated based on the CytoDiffusion model, initially containing 24 explanatory variables (11 morphological, 4 color based, 9 patient clinical). The data were split into 70% training and 30% test sets using stratified sampling. For variable selection, a bidirectional stepwise selection algorithm minimizing the AIC criterion was used, followed by the Wald test to assess the significance of individual coefficients. Multicollinearity was examined using the Variance Inflation Factor (VIF). The stepwise selection automatically resolved the multicollinearity issue by removing one of the highly correlated variables from the model. The final model consisted of 12 statistically significant variables (9 morphological, 3 color based), while all patient clinical variables were excluded from the model. Model performance was evaluated on the test set using sensitivity, specificity, accuracy, F1 score, and AUC-ROC. The optimal decision threshold was determined by the Youden J index and found to be close to the default threshold of 0.50 (0.517). The generalizability of the model was tested using 10-fold cross-validation. The classification performance metrics calculated on the test set showed consistency with the 10-fold cross-validation results. In the odds ratio analysis, the signs and magnitudes of the coefficient estimates provide interpretable information regarding the direction and strength of the effect of each explanatory variable on the response variable. The findings demonstrate that the developed logistic regression model is a statistically valid and interpretable tool for the given classification problem.