A new approach for the synthesis of 2-substituted indole derivatives via Michael type adducts

Çavdar, H; SARAÇOĞLU, NURULLAH

doi:10.1016/j.tet.2005.01.017

A new approach for the synthesis of 2-substituted indole derivatives via Michael type adducts

Çavdar H., SARAÇOĞLU N.

TETRAHEDRON, cilt.61, sa.9, ss.2401-2405, 2005 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 61 Sayı: 9
Basım Tarihi: 2005
Doi Numarası: 10.1016/j.tet.2005.01.017
Dergi Adı: TETRAHEDRON
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC)
Sayfa Sayıları: ss.2401-2405
Ankara Üniversitesi Adresli: Hayır

Özet

4,7-Dihydroindole undergoes regioselective alkylation at the 2-position of the indole nucleus through conjugate addition with alpha,beta-unsaturated carbonyl compounds. The oxidation of the Michael adducts affords the corresponding 2-substituted indole derivatives which were characterized by spectroscopic methods. (C) 2005 Elsevier Ltd. All rights reserved.