Atıf İçin Kopyala
YILDIZ U., ŞENGÜL A., KANDEMİR İ., CÖMERT F., AKKOÇ S., ÇOBAN B.
BIOORGANIC CHEMISTRY, cilt.87, ss.70-77, 2019 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
87
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Basım Tarihi:
2019
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Doi Numarası:
10.1016/j.bioorg.2019.03.009
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Dergi Adı:
BIOORGANIC CHEMISTRY
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.70-77
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Anahtar Kelimeler:
DNA binding, Intercalation, Dicnq, Transcription inhibition, PCR inhibition, Cytotoxicity, Antibacterial susceptibility, MOLECULAR LIGHT SWITCH, TRANSCRIPTION INHIBITION, RUTHENIUM(II) COMPLEXES, COBALT(III), LIGANDS, 6,7-DICYANODIPYRIDOQUINOXALINE, DERIVATIVES, SELECTIVITY, CLEAVAGE
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Ankara Üniversitesi Adresli:
Evet
Özet
The square-planar heteroleptic Pt(II) coordination compound [Pt(bpy)(dicnq)](NO3)(2) (1) and the quaternized dicnq ligand, namely 12,13-dicyano-5,6-dihydrodipyrazino[2,3-f:1',2',3',4'-lmn] [1,10] phenanthroline-4,7-diium dibromide (2) (Fig. 1) were synthesized and fully characterized by means of FTIR, NMR, MALDI-TOF MS and the purity was confirmed by CHN analyses. The DNA binding profiles of 1 and 2 were identified in an identical condition. The biological activities of these compounds were investigated by the assays of transcription and replication inhibition, cytotoxic and antimicrobial activity.