Does anti-oxidant prophylaxis with melatonin prevent adverse outcomes related to increased oxidative stress caused by laparoscopy in experimental rat model?

Cay A., Imamoglu M., ÜNSAL M. A., AYDIN S., Alver A., Akyol A., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.135, sa.1, ss.2-8, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 135 Sayı: 1
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.jss.2005.12.025
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2-8
  • Anahtar Kelimeler: ischemia, reperfusion, increased abdominal pressure, laparoscopy, melatonin, intestine, SMALL-INTESTINE, ISCHEMIA/REPERFUSION INJURY, INTRAABDOMINAL PRESSURES, ISCHEMIA-REPERFUSION, ARTERY-OCCLUSION, PNEUMOPERITONEUM, INSUFFLATION, TISSUE, CO2, CHOLECYSTECTOMY
  • Ankara Üniversitesi Adresli: Hayır

Özet

Background. We hypothesized that prophylaxis with an anti-oxidant should prevent potential adverse outcomes of laparoscopy related to increased oxidative stress in splanchnic organs, including small intestine, liver, and kidneys, and melatonin is the most appropriate agent for this purpose.