Does Structured Withdrawal of Desmopressin Improve Relapse Rates in Patients with Monosymptomatic Enuresis?

GÖKCE, MEHMET; Hajiyev, Parviz; SÜER, EVREN; Kibar, Yusuf; Silay, Mesrur; Gurocak, Serhat; DOĞAN, HASAN; Irkilata, Hasan; Oktar, Tayfun; Onal, Bulent; ERDEM, ERİM; Aygun, Yuksel; Balci, Can; Arslan, Ahmet; Kaya, Cevdet; SOYGÜR, YAKUP; Sarikaya, Saban; TEKGÜL, SERDAR; BURGU, BERK

doi:10.1016/j.juro.2014.01.094

Does Structured Withdrawal of Desmopressin Improve Relapse Rates in Patients with Monosymptomatic Enuresis?

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GÖKCE M. İ., Hajiyev P., SÜER E., Kibar Y., Silay M. S., Gurocak S., ...More

JOURNAL OF UROLOGY, vol.192, no.2, pp.530-534, 2014 (SCI-Expanded)

Publication Type: Article / Article
Volume: 192 Issue: 2
Publication Date: 2014
Doi Number: 10.1016/j.juro.2014.01.094
Journal Name: JOURNAL OF UROLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.530-534
Keywords: deamino arginine vasopressin, enuresis, recurrence, NOCTURNAL ENURESIS, CHILDREN
Ankara University Affiliated: Yes

Abstract

Purpose: Relapse after cessation of desmopressin is an important problem in treating patients with enuresis. Structured withdrawal of desmopressin tablets has been shown to decrease relapse rates. However, scientific data are lacking on the structured withdrawal of the fast melting oral formulation of desmopressin. We compared relapse rates of structured withdrawal using placebo and direct cessation in a population of patients with enuresis who were desmopressin responders.