Evaluation of chronotype and sleep quality in infertile population and comparison with fertile population: a cross-sectional study

Özçelik C., VARLI B., Gökçe A., Takmaz T., ÇETİN Ç., ÖZCAN P.

Journal of psychosomatic obstetrics and gynaecology, vol.44, no.1, pp.2148523, 2023 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 1
  • Publication Date: 2023
  • Doi Number: 10.1080/0167482x.2022.2148523
  • Journal Name: Journal of psychosomatic obstetrics and gynaecology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, Academic Search Premier, PASCAL, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Psycinfo
  • Page Numbers: pp.2148523
  • Keywords: Infertility, sleep quality, MEQ, PSQI, chronotype, DURATION, IMPACT
  • Ankara University Affiliated: Yes


PURPOSE: Infertility is a stressful condition for couples and can affect patients' circadian rhythm and sleep quality. The goal of this study is to assess differences in chronotype and sleep quality between infertile and fertile people. METHODS: A cross-sectional study was conducted. The infertile patient population consisted study group. Primiparous patients without any known gynecological disease who presented for routine cervical cancer screening follow-up were included in the control group. The Turkish version of the Morningness-Eveningness Questionnaire (MEQ) and Pittsburg Sleep Quality Index (PSQI) scores were evaluated between groups. RESULTS: A total of 227 patients were assessed. There were 110 patients in the study (infertile) group and 117 patients in the control (fertile) group. The evening chronotype proportion (23.6 vs. 0.9%, p < 0.001) was higher in the infertile group. The median of MEQ score was significantly higher in the fertile patients (50, IQR = 43 - 55 vs. 56, IQR = 51 - 59; p < 0.001), and the median of PSQI score was significantly higher in the infertile patients (5, IQR = 4 - 6, vs. 4, IQR = 3 - 5; p < 0.001). CONCLUSIONS: In this study, we found significantly worse sleep quality, and more evening chronotype in the patients with infertility.