Akademik Veri Yönetim Sistemi
Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi, cilt.26, sa.2, ss.227-233, 2023 (Hakemli Dergi)
Helianthemum is represented by 19 taxa, and out of four are endemic in Türkiye. The antioxidant, anti-inflammatory, and hypoglycemic activities of the ethanol (75%) and aqueous extracts from aerial parts of Helianthemum oelandicum subsp. incanum growing in Türkiye was examined in this study. The water extract exhibited antioxidant activity with 67.26±0.49 and 68.08±0.41 μg ml-1 values on DPPH and ABTS radicals, respectively. The antioxidant activity value of ethanol extract on DPPH radical was found as 46.71±0.27 μg ml-1, where as this value was determined as 51.60±0.76 μg ml-1 for scavenging effects on ABTS radical. Both ethanol and aqueous extracts possessed in vitro anti- inflammatory activity by inhibiting erythrocyte membrane hemolysis in a concentration dependent manner and ethanol extracts exhibited greater activity than aqueous extracts. By measuring the inhibitory effect of the extracts on α-glucosidase, in vitro hypoglycemic activity was assessed. According to the results of this study, the IC50 values of both ethanolic and aqueous extracts were found to be close to each other, 2.52±0.01 and 3.21±0.01 μg ml-1, respectively and compared with the standard compound acarbose (IC50= 0.90±0.01 μg ml-1) it was determined that both extracts exhibited strong inhibition on α- glucosidase. Based on all results evaluated, the ethanolic extract displayed higher antioxidant, anti-inflammatory, and hypoglycemic activities than the aqueous extract.