Mesenchymal Stem Cells for Coronavirus (COVID-19)-Induced Pneumonia: Revisiting the Paracrine Hypothesis with New Hopes?
AGING AND DISEASE, cilt.11, sa.3, ss.477-479, 2020 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Editöre Mektup
- Cilt numarası: 11 Sayı: 3
- Basım Tarihi: 2020
- Doi Numarası: 10.14336/ad.2020.0403
- Dergi Adı: AGING AND DISEASE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, EMBASE, Directory of Open Access Journals
- Sayfa Sayıları: ss.477-479
- Anahtar Kelimeler: COVID-19, mesenchymal stem cells, cell transplantation, pneumonia, immunomodulation
- Ankara Üniversitesi Adresli: Evet
Özet
Mesenchymal stem cells (MSCs) bear a promising potential for regenerative medicine therapies and they repair damaged tissue through secretion of immune modulatory and anti-inflammatory molecules acting in a paracrine fashion. Coronavirus disease 2019 (COVID-19) has spread all over the world with high morbidity and mortality rates and there is no specific treatment for this infection. A recent study published in the journal reports that MSC infusion is safe and effective in patients suffering from COVID-19 induced pneumonia. In the light of this study and previous reports, we make additional comments about possible therapeutic effects of MSCs in COVID-19 infection.