Effects of isoflurane on nitric oxide metabolism and oxidant status of guinea pig myocardium

Durak I., Kavutcu M., Kacmaz M., Avci A., HORASANLI E., Dikmen B., ...More

ACTA ANAESTHESIOLOGICA SCANDINAVICA, vol.45, no.1, pp.119-122, 2001 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 1
  • Publication Date: 2001
  • Doi Number: 10.1034/j.1399-6576.2001.450118.x
  • Journal Name: ACTA ANAESTHESIOLOGICA SCANDINAVICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.119-122
  • Keywords: heart, isoflurane, nitric oxide, malondialdehyde, ARGININE METHYL-ESTER, FREE-RADICALS, RELAXING FACTOR, VOLATILE ANESTHETICS, REPERFUSION INJURY, ENDOTHELIUM, HALOTHANE, INHIBITION, ENFLURANE, RATS
  • Ankara University Affiliated: Yes

Abstract

Background: Volatile anesthetics (VAs) have been shown to enhance myocardial recovery during reperfusion, the mechanism of which has not been clarified yet. It has been supposed that this effect of VAs may appear through antioxidative mechanisms.