Post-renal transplantation Leser-Trelat sign associated with carcinoma of the gallbladder: A rare association

Kocyigit P., AKAY B. N., Arica E., Anadolu R. Y., Erdem C.

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, cilt.42, sa.6, ss.779-781, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42 Sayı: 6
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1080/00365520701374270
  • Dergi Adı: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.779-781
  • Anahtar Kelimeler: gallbladder carcinoma, Leser-Trelat, renal transplantation, seborrheic keratoses, ACANTHOSIS NIGRICANS, ADENOCARCINOMA
  • Ankara Üniversitesi Adresli: Evet

Özet

The sign of Leser-Trelat represents the sudden appearance of multiple seborrheic keratoses in association with an underlying malignancy. The most common associated neoplasms belong to the gastrointestinal tract, mainly the stomach and colon. In the literature, there is only one case of gallbladder carcinoma associated with the Leser-Trelat sign. Thus, the hallmark of our patient is post- renal transplant malignancy- associated Leser- Trelat, which has not been reported before. Here, we report on a 57- year- old man who presented with a sudden increase in the number and size of seborrheic keratoses, particularly on sun- exposed areas 24 years after renal transplantation. The search for an underlying malignancy showed the presence of an adenocarcinoma of the gallbladder which had metastasized to the liver.