Enzymatic synthesis of benzoin in supercritical carbon dioxide

Celebi N., Yildiz N., Demir A. S., Calimli A.

JOURNAL OF SUPERCRITICAL FLUIDS, cilt.41, sa.3, ss.386-390, 2007 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41 Sayı: 3
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.supflu.2006.12.007
  • Dergi Adı: JOURNAL OF SUPERCRITICAL FLUIDS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.386-390
  • Anahtar Kelimeler: supercritical carbondioxide, Candida cylindracea (CCL), enantiomeric excess (ee), benzoin, enantioselectivity, LIPASE, ESTERIFICATION, ENANTIOSELECTIVITY, BIOCATALYSIS, HYDROLYSIS, CHEMISTRY
  • Ankara Üniversitesi Adresli: Evet

Özet

Enantioselective enzymatic hydrolysis of benzoyl-benzoin catalyzed by Candida cylindracea (CCL) lipase was carried out in SCCO2. It was found that CCL lipase enantioselectively hydrolyzed the (R)-benzoin. The enantiomeric excess of product (ee(p)) was maximized at 35 degrees C near the critical region 90 bar and obtained 61.3% at a 50% conversion. CCL did not catalyze the reaction in an atmospherical condition. (C) 2006 Elsevier B.V. All rights reserved.