Expression of antimicrobial peptides in recurrent adenotonsillitis

DEMİR M. G., AYDIN S., Erdogan B. A., OĞUZTÜZÜN S., KILIÇ M., Barisik N. O.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.41, sa.6, ss.437-442, 2016 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41 Sayı: 6
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1515/tjb-2016-0145
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.437-442
  • Anahtar Kelimeler: Antimicrobial peptides, Adenotonsillitis, Adenotonsillar hypertrophy, Immunohistochemistry, Immune system, CATHELICIDIN, BACTERIA, DEFENSE
  • Ankara Üniversitesi Adresli: Evet

Özet

Background: Recurrent acute tonsillitis is one of the most frequent otorhinolaryngology clinic referrals, yet its pathogenesis remains poorly understood. Antimicrobial cationic peptides are components of the innate system. They are generally small, highly positively charged peptides with broad spectrum antimicrobial activity which function as the body's "natural antibiotics". Our aim is to investigate the role of antimicrobial cationic peptides in the susceptibility of patients to recurrent acute tonsillitis.