Free radical scavenging abilities of flavonyl-thiazolidine-2,4-dione compounds

Bozdaǧ-Düdar O., Ertan R., Aboul-Enein H. Y., Kładna A., Kruk I.

LUMINESCENCE, cilt.26, sa.1, ss.10-16, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 1
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1002/bio.1176
  • Dergi Adı: LUMINESCENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.10-16
  • Anahtar Kelimeler: flavone, flavonyl-thiazolidine-2,4-dione compounds, free radicals, scavenging capacity, DPPH-CENTER-DOT, ANTIOXIDANT ACTIVITY, OXIDATIVE STRESS, OXYGEN, SUPEROXIDE, IMPAIRMENT, FLAVONOIDS, CHEMISTRY, EXTRACTS, EVALUATE
  • Ankara Üniversitesi Adresli: Evet

Özet

Free radical scavenging activity of flavonyl-thiazolidine-2,4-dione compounds has been evaluated using chemiluminescence, electron spin resonance spectroscopy with 5,5-dimethyl-1-pyrroline-1-oxide as spin trap and DPPH (2,2'diphenyl-1-picrylhydrazyl) method. The examined compounds exhibited 28-50% scavenging superoxide anion radical (O-2((center dot) over bar)), 16.7-76.7% hydroxyl radical (HO center dot) and 9-40% DPPH radical. Compounds containing carbonyl group in their structure can be considered as antioxidants with high relevance and great biological importance. Copyright (C) 2009 John Wiley & Sons, Ltd.