POEMS syndrome: A case report

Oezden A., Sueleyman Z., Seven G., Arat M., Akin A., Sener O., ...More

TURKISH JOURNAL OF GASTROENTEROLOGY, vol.19, no.4, pp.276-280, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 4
  • Publication Date: 2008
  • Journal Name: TURKISH JOURNAL OF GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.276-280
  • Keywords: POEMS syndrome, proteinuria, hypertrophic osteoarthropathy, STEM-CELL TRANSPLANTATION
  • Ankara University Affiliated: Yes

Abstract

A 43-year-old female patient admitted with a 2.5-year history of lower extremity symmetrical sensorimotor polyneuropathy, hypertrichosis, sweating, diarrhea, weight loss, and hyperpigmentation. The clinical evaluation met the criteria for the diagnosis of POEMS syndrome. The patient was initially treated with prednisolone and responded well. We planned high-dose chemotherapy with autologous stem cell rescue and introduced a more immunosuppressive regimen containing cyclophosphamide and dexamethasone. We present a case differing from, the other cases with her 2 g/day proteinuria and hypertrophic osteoarthropathy.