Role of the peritrophic matrix in insect-pathogen interactions
JOURNAL OF INSECT PHYSIOLOGY, cilt.117, 2019 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 117
- Basım Tarihi: 2019
- Doi Numarası: 10.1016/j.jinsphys.2019.103894
- Dergi Adı: JOURNAL OF INSECT PHYSIOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Ankara Üniversitesi Adresli: Evet
Özet
The peritrophic matrix (PM) is an acellular chitin and glycoprotein layer that lines the invertebrate midgut. The PM has long been considered a physical as well as a biochemical barrier, protecting the midgut epithelium from abrasive food particles, digestive enzymes and pathogens infectious per os. This short review will focus on the latter function, as a barrier to pathogens infectious per os. We focus on the evidence confirming the role of the PM as protective barrier against pathogenic microorganisms of insects, mainly bacteria and viruses, as well as the evolution of a variety of mechanisms used by pathogens to overcome the PM barrier.