Species distribution of yeasts isolated from patients with vulvovaginal candidiasis and detection of their antifungal susceptibilities Vulvovajinal kandidiazisli olgulardan izole edilen maya turlerinin dagilimi ve antifungallere duyarliliklarinin saptanmasi

KARAARSLAN A., Cengiz L., Boyacioglu I., CENGİZ A., Ozsan M.

Mikrobiyoloji Bulteni, cilt.33, sa.4, ss.319-325, 1999 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 4
  • Basım Tarihi: 1999
  • Dergi Adı: Mikrobiyoloji Bulteni
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.319-325
  • Anahtar Kelimeler: Antifungal susceptibility, Candida spp., Vaginal discharge
  • Ankara Üniversitesi Adresli: Evet

Özet

In this study, the species distribution and antifungal susceptibilities of yeasts isolated from vaginal swab specimens of 248 patients who applied with complaints of vaginal discharge at Ankara University Hospital, Obstetrics and Gynecology Outpatient Clinics were investigated. A total of 90 (36.3%) yeast strains were isolated by cultivation methods. Sixtynine of them (76.7%) were identified as C. albicans, 10 (11.1%) of C. glabrata, 10 of (11.1%) C. krusei and 1 (1.1%) of C. rugosa by Fungichrom I® identification method. Antifungal susceptibilities of Candida species to amphotericin B (AB), flucytosine (FCT), miconazole (MCZ), econazole (ECZ), ketoconazole (KTZ) and nystatine (NYS) were evaluated by Candifast® test. It was detected that 34.8% of C. albicans isolates were susceptible to MCZ, 24.6% to ECZ and 100% to other antifungal agents, while C. glabrata strains were resistant to MCZ, ECZ and NYS with a rate of 10%, and the susceptibility rate to the others were 100 percent. It was determined that all C. krusei strains were sensitive to FCT, but the resistance rates varied 10% to 30% against other antifungal agents. C. rugosa was found resistant to all tested antifungals.