Akademik Veri Yönetim Sistemi
Revue de Medecine Veterinaire, cilt.157, sa.2, ss.68-71, 2006 (SCI-Expanded)
In this experimental study, the hematological effects of pulsed electromagnetic fields (EMF) chronic exposure were investigated on mice. Sixty, 6 week old male Swiss mice, weighing 40-45g were used, and were divided into two groups: in one group, animals (n=30) were exposed to pulsed EMF (60 Hz, intensity 3μT, twelve hours by day) for a 120 day-period, whereas the second group (n=30) was used as control. On days 15, 30, 90 and 120, samples were taken by cardiac puncture for the hematological analysis (Red blood cell and white blood cell counts, leukocyte distribution). Whereas no significant difference was noted between control and exposed animals at the 15th and the 30th days, a macrocytic anemia characterized by decreases of hemoglobin concentration, hematocrit values and erythrocyte counts and by the increase of mean corpuscular volume, occurred in the exposed animals on day 90. Furthermore, they have shown significant reductions of leukocyte, lymphocyte and neutrophil counts, while monocyte counts were increased. On day 120, these leukocyte alterations were still observed, whereas erythrocyte parameters became close to control values. These results suggest that pulsed electromagnetic fields (60 Hz and 3μT) affect the hematological parameters of mice, probably by reducing proliferation and differentiation of marrow stem cells.