The effects of sodium butyrate and high-performance inulin supplementation on the promotion of gut bacterium Akkermansia muciniphila growth and alterations in miR-375 and KLF5 expression in type 2 diabetic patients: A randomized, double-blind, placebo-controlled trial

Roshanravan, Neda; Mahdavi, Reza; Jafarabadi, Mohammad; Alizadeh, Effat; Ghavami, Abed; Saadat, Yalda; Alamdari, Naimeh; Dastouri, MOHAMMADREZA; Alipour, Shahriar; Ostadrahimi, Alireza

doi:10.1016/j.eujim.2017.12.011

The effects of sodium butyrate and high-performance inulin supplementation on the promotion of gut bacterium Akkermansia muciniphila growth and alterations in miR-375 and KLF5 expression in type 2 diabetic patients: A randomized, double-blind, placebo-controlled trial

Roshanravan N., Mahdavi R., Jafarabadi M. A., Alizadeh E., Ghavami A., Saadat Y. R., ...Daha Fazla

EUROPEAN JOURNAL OF INTEGRATIVE MEDICINE, cilt.18, ss.1-7, 2018 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 18
Basım Tarihi: 2018
Doi Numarası: 10.1016/j.eujim.2017.12.011
Dergi Adı: EUROPEAN JOURNAL OF INTEGRATIVE MEDICINE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1-7
Anahtar Kelimeler: High performance inulin, Sodium butyrate, KLF5, miR-375, Akkermansia muciniphila, Randomised controlled trial, LIPID PROFILE, MICRORNAS, MICROBIOTA, SECRETION, MUCOSAL, PCR
Ankara Üniversitesi Adresli: Evet

Özet

Introduction: The aim of this study is to evaluate the effect of sodium butyrate and High-Performance (HP) inulin supplementation on the promotion of gut bacterium Akkermansia muciniphila growth and alterations in microRNA-375 and Kruppel-like factor 5 (KLF5) expression in patients with T2D.