NOD2/CARD15, NOD1/CARD4, and ICAM-1 gene polymorphisms in Turkish patients with inflammatory bowel disease

Ozen, Senem; Dagli, Ulku; Kilic, Mesut; TÖRÜNER, MURAT; Celik, Yasemin; Ozkan, Muhip; Soykan, ARİF; Cetinkaya, Hulya; Ulker, Aysel; Ozden, Ali; Bozdayi, A.

doi:10.1007/s00535-005-1780-z

NOD2/CARD15, NOD1/CARD4, and ICAM-1 gene polymorphisms in Turkish patients with inflammatory bowel disease

Ozen S. C., Dagli U., Kilic M. Y., TÖRÜNER M., Celik Y., Ozkan M., ...Daha Fazla

JOURNAL OF GASTROENTEROLOGY, cilt.41, sa.4, ss.304-310, 2006 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 41 Sayı: 4
Basım Tarihi: 2006
Doi Numarası: 10.1007/s00535-005-1780-z
Dergi Adı: JOURNAL OF GASTROENTEROLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.304-310
Anahtar Kelimeler: Crohn's disease, ICAM, inflammatory bowel disease, NOD/CARD, ulcerative colitis, ADHESION MOLECULE-1 GENE, NF-KAPPA-B, CROHNS-DISEASE, SUSCEPTIBILITY LOCI, JAPANESE PATIENTS, BEHCETS-DISEASE, NOD2 VARIANTS, FAMILY-MEMBER, ASSOCIATION, POPULATION
Ankara Üniversitesi Adresli: Evet

Özet

Purpose. The genetic susceptibility of people with certain NOD2/CARD15, NOD1/CARD4, and ICAM-1 gene variants to inflammatory bowel disease is still under investigation. The aim of this study was to investigate polymorphisms in the NOD2/CARD15 (R702W, G908R, and 3020insC), NOD1/CARD4 (E266K, D372N), and ICAM-1 (G241R, K469E) genes, which are known to be associated with inflammation, in Turkish patients with inflammatory bowel disease and healthy control groups.