Akademik Veri Yönetim Sistemi
Modern Healt Sciences: Theory, Methodology and Practice, Prof. Ahmet Aslan and Assoc. Prof. Fatih Yücedağ, Editör, Platanus Publishing, Ankara, ss.271-292, 2025
This study models the physical interactions of helium ions accelerated withinthe 170–210 MeV energy range in thyroid tissue and surrounding anatomicalstructures using SRIM/TRIM simulations. The developed tissue model is basedon real anatomical and histological parameters, incorporating structures such asskin, adipose tissue, muscle, trachea, and bone to construct a clinically realisticgeometry. As a result, the simulations generated highly reliable data critical forradiotherapy applications, including ion energy loss (Bragg peak), rangedistribution, lateral scattering, and microscopic damage (DPA and recoil).Simulation results revealed that the penetration range of helium ions increaseswith energy by approximately 1.09% to 1.95%, the Bragg peak can be preciselypositioned within the thyroid tissue, and adjacent healthy tissues can beeffectively spared. Furthermore, the low degree of lateral scattering and thehomogeneity of the linear energy transfer (LET) profile enable accurate and safedose distributions, particularly for thyroid tumors located near vital structuressuch as the trachea and esophagus. Recoil energy curves and DPA analysesdemonstrated that the extent of microscopic structural damage is energy-dependent, with maximum DPA occurring at depths ranging from 169.2 mm to187.2 mm for energies between 171 and 180 MeV.