A Turkish 3-center study evaluation of serum folic acid and vitamin B12 levels in Alzheimer disease

Ulusu N. N., Yilmaz G., Erbayraktar Z., EVLİCE A. T., ARAS S., Yener G., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.45, sa.5, ss.1159-1166, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 5
  • Basım Tarihi: 2015
  • Doi Numarası: 10.3906/sag-1406-136
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1159-1166
  • Anahtar Kelimeler: Alzheimer disease, vitamin B12, folic acid, COGNITIVE DECLINE, DEMENTIA, PLAQUES, PROTEIN, BRAIN
  • Ankara Üniversitesi Adresli: Evet

Özet

Background/aim: Alzheimer disease, a common proteopathy of advanced age, is characterized by cortical atrophy, neuron degeneration, neuronal loss, and accumulation of extracellular amyloid beta plaques. We aimed to investigate serum vitamin B12 and folic acid levels in Alzheimer disease and other dementia patients, as a potential screening test to detect presymptomatic Alzheimer disease in Turkish patients.