Increased Circulatory Extrarenal 1 alpha,25-Dihydroxyvitamin D3 in Bilaterally Nephrectomized Rats

DABAK M., DABAK D. Ö., KULOĞLU T., BAYDAR E., BULUT H., Ozoner O.

ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, vol.20, no.9, pp.1523-1530, 2020 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 9
  • Publication Date: 2020
  • Doi Number: 10.2174/1871530320666200530222426
  • Journal Name: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, BIOSIS, Biotechnology Research Abstracts, EMBASE, MEDLINE
  • Page Numbers: pp.1523-1530
  • Keywords: 1 alpha,25-dihydroxyvitamin D-3, 25-hydroxyvitamin D, inflammation, extrarenal, anephric, rat, CULTURED ALVEOLAR MACROPHAGES, 1,25-DIHYDROXYVITAMIN-D3 PRODUCTION, SKELETAL RESISTANCE, PARATHYROID-HORMONE, VITAMIN-D3, EXPRESSION, RECEPTORS, PHARMACOKINETICS, IDENTIFICATION, METABOLITES
  • Ankara University Affiliated: Yes

Abstract

Background: Extrarenal 1 alpha,25-dihydroxyvitamin D-3 (1,25-D) locally produced by immune cells plays crucial roles in the regulation of the immune system. However, in vivo status of extrarenal 1,25-D and 25-hydroxyvitamin D (25-D) in acute inflammatory conditions are unknown.