A histopathologic investigation on the effects of electrical stimulation on periodontal tissue regeneration in experimental bony defects in dogs

Kaynak D., Meffert R., Gunhan M., Gunhan B.

JOURNAL OF PERIODONTOLOGY, vol.76, no.12, pp.2194-2204, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 76 Issue: 12
  • Publication Date: 2005
  • Doi Number: 10.1902/jop.2005.76.12.2194
  • Journal Name: JOURNAL OF PERIODONTOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2194-2204
  • Keywords: alveolar bone loss, bone formation, electrical stimulation/therapeutic use, osteogenesis, regeneration, AFIBRILLAR ACELLULAR CEMENTUM, ALKALINE-PHOSPHATASE ACTIVITY, MUCOPERIOSTEAL FLAP SURGERY, TOOTH MOVEMENT, BISPHOSPHONATE ALENDRONATE, ACCELERATED REATTACHMENT, MORPHOGENETIC PROTEIN-2, BIOELECTRIC POTENTIALS, ELECTROMAGNETIC-FIELDS, LIGAMENT FIBROBLASTS
  • Ankara University Affiliated: Yes

Abstract

Background: One endpoint of periodontal therapy is to regenerate the structure lost due to periodontal disease. In the periodontium, gingival epithelium is regenerated by oral epithelium. Underlying connective tissue, periodontal ligament, bone, and cementum are derived from connective tissue. Primitive connective tissue cells may develop into osteoblasts and cementoblasts, which form bone and cementum. Several procedural advances may support these regenerations; however, the regeneration of alveolar bone does not always occur. Therefore, bone stimulating factors are a main topic for periodontal reconstructive research. The present study was designed to examine histopathologically whether the application of an electrical field could demonstrate enhanced alveolar and cementum regeneration and modify tissue factors.