Effect of Hepatosteatosis on the Virological Response in Entecavir and Tenofovir Therapies

KORKMAZ, PINAR; Demirturk, Nese; Batirel, Ayse; Tulek, Necla; Ozguler, Muge; Harman, Rezan; ÇINAR, GÜLE; TOKA, ONUR; Yoruk, Gulsen; Ataman-Hatipoglu, Cigdem; Sarigul, Figen; SIRMATEL, FATMA; Imre, Ayfer; MISTANOĞLU ÖZATAĞ, DURU; KARAKEÇİLİ, FARUK; URAL, ONUR; SÜMER, ŞUA; Aktug-Demir, Nazlim; Kadanali, Ayten; Comoglu, Senol; Ucer, Sengul; SALTOĞLU, NEŞE; Gunal, Ozgur; Ozkaya, Hacer; Yenilmez, Ercan; Cetinkaya, Riza; Yuksel, Esma; Hakyemez, Ismail; MERİÇ KOÇ, MELİHA; Tuncer-Ertem, Gunay; Bestepe-Dursun, Zehra; Celik, Ilhami; YILMAZ, EMEL; Evik, Guliz; Kaya, Ali; Suer, Kaya

doi:10.5152/kd.2019.73

Effect of Hepatosteatosis on the Virological Response in Entecavir and Tenofovir Therapies

Atıf İçin Kopyala

KORKMAZ P., Demirturk N., Batirel A., Tulek N., Ozguler M., Harman R., ...Daha Fazla

KLIMIK JOURNAL, cilt.32, sa.3, ss.265-274, 2019 (ESCI)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 32 Sayı: 3
Basım Tarihi: 2019
Doi Numarası: 10.5152/kd.2019.73
Dergi Adı: KLIMIK JOURNAL
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
Sayfa Sayıları: ss.265-274
Anahtar Kelimeler: Fatty liver, entecavir, tenofovir, CHRONIC HEPATITIS-B, FATTY LIVER-DISEASE, VIRUS INFECTION, STEATOSIS, IMPACT, PREVALENCE, ANTIGEN, HOST
Ankara Üniversitesi Adresli: Hayır

Özet

Objective: Both chronic hepatitis B (CHB) and hepatosteatosis may lead to necroinflammation in liver. Therefore, the presence of hepatosteatosis might negatively affect the efficacy of antiviral therapy. We aimed to determine the effect of hepatosteatosis on virological response in patients with CHB receiving entecavir (ETV) and tenofovir (TDF) treatment.