Comparative Study for the Determination of Gemifloxacin by HPLC and Microbiological Methods from Pharmaceutical Preparations and Biological Samples
CURRENT PHARMACEUTICAL ANALYSIS, cilt.11, sa.3, ss.193-200, 2015 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 11 Sayı: 3
- Basım Tarihi: 2015
- Doi Numarası: 10.2174/1573412911666150305001657
- Dergi Adı: CURRENT PHARMACEUTICAL ANALYSIS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.193-200
- Anahtar Kelimeler: Gemifloxacin, HPLC, microbiology, validation, biological samples, pharmaceuticals, LIQUID-CHROMATOGRAPHY, DOSAGE FORMS, HUMAN SERUM, MESYLATE, FORMULATIONS, ASSAY, BULK, PHARMACOKINETICS, SUSCEPTIBILITY, VALIDATION
- Ankara Üniversitesi Adresli: Evet
Özet
The fluoroquinolones have broad-spectrum activity, good absorption in gastrointestinal canals and superior tissue penetration. Because of these properties, they have been used to treat a wide range of infections. In this study high performance, liquid chromatography and microbiological methods have been developed for the determination of Gemifloxacin (GEM) in pharmaceutical preparations and human plasma.