Using dimensional models of externalizing psychopathology to aid in gene identification

Dick D. M., Aliev F., Wang J. C., Grucza R. A., Schuckit M., Kuperman S., ...Daha Fazla

ARCHIVES OF GENERAL PSYCHIATRY, cilt.65, sa.3, ss.310-318, 2008 (SCI-Expanded, SSCI, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 65 Sayı: 3
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1001/archpsyc.65.3.310
  • Dergi Adı: ARCHIVES OF GENERAL PSYCHIATRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Sayfa Sayıları: ss.310-318
  • Ankara Üniversitesi Adresli: Evet

Özet

Context: Twin studies provide compelling evidence that alcohol and drug dependence, childhood conduct disorder, adult antisocial behavior, and disinhibitory personality traits share an underlying genetic liability that contributes to a spectrum of externalizing behaviors. However, this information has not been widely used in gene identification efforts, which have focused on specific disorders diagnosed using traditional psychiatric classification systems.