Alterations in hippocampal neurogenesis and hippocampal insulin signaling pathway in rat with metabolic syndrome

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Bayram P., BİLLUR D., KIZIL Ş., Caliskan H., CAN B.

IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, cilt.25, sa.11, ss.1308-1316, 2022 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 11
  • Basım Tarihi: 2022
  • Doi Numarası: 10.22038/ijbms.2022.64917.14295
  • Dergi Adı: IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, Index Islamicus, Veterinary Science Database, Directory of Open Access Journals
  • Sayfa Sayıları: ss.1308-1316
  • Anahtar Kelimeler: Behavior tests, Hippocampus, Immunohistochemistry, Insulin, Metabolic syndrome, Neurogenesis, RESISTANCE, DIFFERENTIATION, TRANSLOCATION, RECEPTOR, MODEL
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective(s): We aimed to examine the level of hippocampal neurogenesis, and assess learning and anxiety and the level of some proteins involving insulin signaling pathways in rats with Metabolic Syndrome (MetS); and to reveal the relationship among them.