The fate of recipient-derived hepatocytes in sex-mismatched liver allograft following liver transplantation
CLINICAL TRANSPLANTATION, cilt.21, sa.2, ss.202-206, 2007 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 21 Sayı: 2
- Basım Tarihi: 2007
- Doi Numarası: 10.1111/j.1399-0012.2006.00623.x
- Dergi Adı: CLINICAL TRANSPLANTATION
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.202-206
- Anahtar Kelimeler: hepatocyte, liver transplantation, regenerative medicine, repopulation, stem cells, BONE-MARROW-CELLS, STEM-CELLS, FUSION, MICROCHIMERISM, MICE, REGENERATION
- Ankara Üniversitesi Adresli: Evet
Özet
Background: ''Bone marrow-derived stem cells'' have attracted great attention as potential candidates for liver-directed gene therapy and as a tool for regenerative medicine. However, the fate of these cells is not well-known. The aim of this present study was to investigate the fate of ''recipient-derived repopulated hepatocytes'' in sex-mismatched liver allografts in individuals following liver transplantation during systematic longitudinally performed liver biopsies.