Akademik Veri Yönetim Sistemi
HRU International Journal of Dentistry and Oral Research, cilt.5, sa.1, ss.40-44, 2025 (Hakemli Dergi)
Regenerative endodontic therapy represents an innovative treatment approach designed to restore the physiological functions of the pulp-dentin complex and facilitate continued root development in immature teeth with necrotic pulp. This method holds promise for reducing the risk of fractures in immature teeth by encouraging the thickening of the root canal structures and facilitating ongoing root development. This case report details a 24-month follow-up of an immature permanent tooth with necrotic pulp managed using a regenerative endodontic treatment approach. As part of the regenerative endodontic treatment protocol, 1.5% sodium hypochlorite and 17% ethylenediaminetetraacetic acid were used as irrigation solution, and a dual antibiotic paste (1:1 ciprofloxacin: metronidazole) was applied as intracanal medication. Following the induction of bleeding into the root canal, mineral trioxide aggregate was placed as a coronal plug over the formed blood clot, and the tooth was subsequently restored with composite resin material. At the 24-month clinical and radiographic assessment, the tooth exhibited a favorable response to cold and electric pulp testing, with no signs of sensitivity upon percussion or palpation. Periapical radiographs showed resolution of the periapical lesion and indicated ongoing root development. In conclusion, regenerative endodontic therapy offers a promising substitute for traditional apexification, particularly for immature permanent teeth, by promoting the thickening of the root canal structures and supporting the restoration of the tooth's physiological function.