Evaluation of salivary and serum methylated arginine metabolites and nitric oxide synthase in advanced periodontitis patients

Sengul, Volkan; GÜNEY, ZELİHA; KURGAN, ŞİVGE; ÖNDER, CANAN; SERDAR, Muhittin; GÜNHAN, MERAL

doi:10.1007/s00784-022-04479-w

Evaluation of salivary and serum methylated arginine metabolites and nitric oxide synthase in advanced periodontitis patients

Sengul V., GÜNEY Z., KURGAN Ş., ÖNDER C., SERDAR M. A., GÜNHAN M.

CLINICAL ORAL INVESTIGATIONS, cilt.26, sa.7, ss.5061-5070, 2022 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 26 Sayı: 7
Basım Tarihi: 2022
Doi Numarası: 10.1007/s00784-022-04479-w
Dergi Adı: CLINICAL ORAL INVESTIGATIONS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
Sayfa Sayıları: ss.5061-5070
Anahtar Kelimeler: Asymmetric dimethylarginine (ADMA), Periodontitis, Nitric oxide synthase (NOS), ASYMMETRIC DIMETHYLARGININE ADMA, ENDOTHELIAL DYSFUNCTION, OXIDATIVE STRESS, ENDOGENOUS METHYLARGININES, CARDIOVASCULAR-DISEASES, NO, INHIBITOR, SMOKING, RELEASE, COMPLEX
Ankara Üniversitesi Adresli: Evet

Özet

Objectives Methylated arginine metabolites and nitric oxide synthase (NOS) play a critical role in regulating endothelial function. The aim of this study was to determine levels of NOS, and methylated arginine metabolites (ADMA, SDMA, homoarginine, arginine, and L-NMMA) and IL-6 in serum and saliva in patients with advanced periodontal diseases and identify their association with clinical parameters.