Annexin V Expression and Anti-Annexin V Antibodies in Type 1 Diabetes

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BAKAR ATEŞ F., ÜNLÜTÜRK U., Baskal N., Nebioglu S.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, cilt.99, sa.3, ss.932-937, 2014 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 99 Sayı: 3
• Basım Tarihi: 2014
• Doi Numarası: 10.1210/jc.2013-2592
• Dergi Adı: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.932-937
• Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
• Ankara Üniversitesi Adresli: Evet

Özet

Background: Annexin V (AnxV) has potent anticoagulant properties and regulatory functions for apoptosis and inflammation. Antibodies against annexin V (anti-AnxVs) may inhibit AnxV functions, leading to thrombosis during autoimmune diseases. Type 1 diabetes is an autoimmune disease and related with an ongoing autoimmune inflammation and thrombotic complications. There is no study evaluating anti-AnxVs/AnxV in a disease setting.