Annexin V Expression and Anti-Annexin V Antibodies in Type 1 Diabetes

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BAKAR ATEŞ F., ÜNLÜTÜRK U., Baskal N., Nebioglu S.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, vol.99, no.3, pp.932-937, 2014 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 99 Issue: 3
• Publication Date: 2014
• Doi Number: 10.1210/jc.2013-2592
• Journal Name: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.932-937
• Ankara University Affiliated: Yes

Abstract

Background: Annexin V (AnxV) has potent anticoagulant properties and regulatory functions for apoptosis and inflammation. Antibodies against annexin V (anti-AnxVs) may inhibit AnxV functions, leading to thrombosis during autoimmune diseases. Type 1 diabetes is an autoimmune disease and related with an ongoing autoimmune inflammation and thrombotic complications. There is no study evaluating anti-AnxVs/AnxV in a disease setting.