Plasminogen activator inhibitor-1 (PAI-1) gene polymorphism (-675 4G/5G) associated with obesity and vascular risk in children

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Atıf İçin Kopyala

BERBEROĞLU M., EVLİYAOĞLU S. O., Adiyaman P., Ocal G., ULUKOL B., Simsek F., ...Daha Fazla

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.19, sa.5, ss.741-748, 2006 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 19 Sayı: 5
• Basım Tarihi: 2006
• Dergi Adı: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.741-748
• Anahtar Kelimeler: PAI-1 gene polymorphism, childhood obesity, vascular disease, INSULIN-RESISTANCE, OVERWEIGHT PREVALENCE, ADOLESCENTS, MORTALITY, TRENDS
• Ankara Üniversitesi Adresli: Evet

Özet

Atherothrombotic complications in insulin resistance are partly attributed to impaired fibrinolysis caused by increased PAI-1 plasma levels, and 4G/5G promotor polymorphism of the PAI-1 gene may modulate PAI-1 transcription.