Akademik Veri Yönetim Sistemi
Turkish Journal of Gastroenterology, cilt.9, sa.4, ss.388-393, 1998 (SCI-Expanded)
A 60 year old man presented to our service with a three month history of severe constipation, abdominal pain, headache and vertigo. A one month history of hearing Logs, conjunctival hyperemia and visual disturbance was also reported. A 3.5 cm in diameter, homogenous, radiopaque mass was seen in the left suprarenal gland on CT scan and pseudotumor cerebri was diagnosed. Also, MRI of the left suprarenal gland documented a hypodense lesion, 33 30 mm in diameter, with axial sections on TIAG. Following three days of appropriate diet results of 24 hour urine collection for vanillylmandelic acid (VMA) and metanefrin levels were 17.1, 9.1 (normal 1-8 mg/24 hrs) and 1.1, 1.5 (normal 0.00-1.00 mg/24 hrs) respectively. Whole-bodys cintigraphy with 1-131 metiliodobenzylguanidin (MIBG) did not show any uptake over the suprarenal mass. Clinical and laboratory findings were not consistent with pheochromocytoma. The suprarenal mass was removed surgically and histopathologic and immunohistochemical studies such as chromogranin A (++) and S 100 (+) were suggestive of pheochromocytoma. We observed remarkable improvement of clinical and laboratory findings following surgery. Due to elevated levels of sedimentation rate, C reactive protein (CRP) and ferritin, we speculated that uveitis most likely developed in this patient due to an autoimmune mechanism. In our extensive literature search, we did not come across any case of pheochromocytoma associated with pseudotumor cerebri and uveitis.