Peritumoral brain edema in intracranial meningiomas

Gurkanlar D., Er U., Sanli M., Ozkan M. M., Sekerci Z.

JOURNAL OF CLINICAL NEUROSCIENCE, vol.12, no.7, pp.750-753, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 7
  • Publication Date: 2005
  • Doi Number: 10.1016/j.jocn.2004.09.029
  • Journal Name: JOURNAL OF CLINICAL NEUROSCIENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.750-753
  • Keywords: meningioma, peritumoral brain edema, edema index, age, CEREBRAL EDEMA, RECEPTORS, TUMORS, MRI
  • Ankara University Affiliated: Yes

Abstract

Objective. The goal of this study was to determine the relationship between patient age and gender and meningioma location, histological subtype, size, lobulation and peritumoral brain edema (PTBE). Patients and methods. In a series of 55 patients with intracranial meningiomas, factors possibly related to the development of PTBE were analyzed. We used an El (edema index) as the indicator of PTBE. El was calculated by dividing the area of PTBE by that of the tumor. Thus if El = 1, there is no PTBE. Univariate analysis was used to evaluate the relationship between El and related factors. The MEI (mean edema index) difference between age groups was calculated using the Duncan Test. Results. We found that none of the factors analyzed influenced PTBE except patient age 61-70 years, which correlated with PTBE (p=0.022). The difference between MEI in the 41-50 years and 61-70 years age groups was significant, with that in the 61-70 years age group being significantly higher. Conclusion. We conclude that these findings in the 61-70 years age group may constitute an increased risk of perioperative mortality and morbidity. (c) 2005 Elsevier Ltd. All rights reserved.