The reactions of 2-trans-6-bis(4-fluorobenzyl)spirocyclotetraphosphazene with primary amines: spectroscopic and crystallographic characterizations

ELMAS G.

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, cilt.192, sa.11, ss.1224-1232, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 192 Sayı: 11
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1080/10426507.2017.1359595
  • Dergi Adı: PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1224-1232
  • Anahtar Kelimeler: 2-Trans-6-bis-(4-fluorobenzyl)spirocyclotetraphosphazenes, substitution reactions, spectroscopy, cystallography, PHOSPHORUS-NITROGEN COMPOUNDS, DNA INTERACTIONS, CYTOTOXIC ACTIVITIES, STEREOGENIC PROPERTIES, BIOLOGICAL-ACTIVITIES, STRUCTURAL CHARACTERIZATIONS, CRYSTAL-STRUCTURES, SPIRO, ANTITUBERCULOSIS, MONO
  • Ankara Üniversitesi Adresli: Evet

Özet

The substitution reactions of 2-trans-6-bis(4-fluorobenzyl)spirocyclotetraphosphazene (3; with a yield of 59%) are carried out with excess alkylamines, benzylamine, n-hexylamine, n-butylamine, n-propylamine and iso-propylamine in THF. As a result of these reactions, the fully substituted tetrabenzylamino (3a), tetrahexylamino (3b), tetrabutylamino (3c), tetrapropylamino (3d), and tetraisopropylamino (3e) 2-trans-6-bis-(4-fluorobenzyl)spirocyclotetraphosphazenes are obtained in high yields. The structural characterizations of the isolated compounds (3a-3e) were confirmed by elemental analyses, mass spectrometry (ESI-MS), Fourier transform infrared (FTIR), heteronuclear single quantum coherence (HSQC), heteronuclear multiple-bond correlation (HMBC) and H-1, C-13{H-1}, P-31{H-1} NMR techniques. The solid state and molecular structures of 3a were determined using X-ray crystallography. Two independent molecules were present in its unit cell.