Comparison of 1 mg and 2 mg Overnight Dexamethasone Suppression Tests for the Screening of Cushing's Syndrome in Obese Patients

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ŞAHİN M., Kebapcilar L., Taslipinar A., Azal O., Ozgurtas T., Corakci A., ...More

INTERNAL MEDICINE, vol.48, no.1, pp.33-39, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 1
  • Publication Date: 2009
  • Doi Number: 10.2169/internalmedicine.48.1234
  • Journal Name: INTERNAL MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.33-39
  • Keywords: Cushing's syndrome (CS), obesity, insulin resistance, 1 mg / 2 mg overnight dexamethasone suppression test, DIFFERENTIAL-DIAGNOSIS, DIABETIC-PATIENTS, CIRCADIAN-RHYTHM, CORTISOL, PLASMA
  • Ankara University Affiliated: No

Abstract

Objective Obesity is currently a major public health problem and one of the potential underlying causes of obesity in a minority of patients is Cushing's syndrome (CS). Traditionally, the gold standard screening test for CS is 1 mg dexamethasone overnight suppression test. However, it is known that obese subjects have high false positive results with this test.