Electrochemical glucose biosensor based on nickel oxide nanoparticle-modified carbon paste electrode

Erdem C., KOYUNCU ZEYBEK D., AYDOĞDU TIĞ G., ZEYBEK B., Pekyardimci S., Kilic E.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY, cilt.42, sa.4, ss.237-244, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42 Sayı: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.3109/21691401.2013.808649
  • Dergi Adı: ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.237-244
  • Anahtar Kelimeler: amperometric glucose biosensor, carbon paste electrode, glucose oxidase, nickel oxide nanoparticles, ELECTROCATALYTIC ACTIVITY, PLATINUM-ELECTRODE, ASCORBIC-ACID, HUMAN SERUM, IN-VITRO, IMMOBILIZATION, NIO, FILM, NANOTUBE, SENSORS
  • Ankara Üniversitesi Adresli: Evet

Özet

In the present work, we designed an amperometric glucose biosensor based on nickel oxide nanoparticles (NiONPs)-modified carbon paste electrode. The biosensor was prepared by incorporation of glucose oxidase and NiONPs into a carbon paste matrix. It showed good analytical performances such as high sensitivity (367 mu A mmolL(-1)) and a wide linear response from 1.9 x 10(-3) mmolL(-1) to 15.0 mmolL(-1) with a limit of detection (0.11 mu molL(-1)). The biosensor was used for the determination of glucose in human serum samples. The results illustrate that NiONPs have enormous potential in the construction of biosensor for determination of glucose.