Behcet's syndrome and relationship with the ratio of insulin-like growth factor-1 (IGF-1)/IGF-binding protein-3 (IGFBP-3)

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DOĞAN Ö., Unal E., KISA Ü., Aksoy N.

POSTEPY DERMATOLOGII I ALERGOLOGII, cilt.36, sa.3, ss.295-301, 2019 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 3
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5114/ada.2019.85640
  • Dergi Adı: POSTEPY DERMATOLOGII I ALERGOLOGII
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.295-301
  • Anahtar Kelimeler: Behcet's syndrome, insulin like growth factor-1, IGF-binding protein-3, inflammation, IGF-1/IGFBP-3 MOLAR RATIO, IGF-BINDING PROTEIN-3, SERUM-LEVELS, RESISTANCE, RESTRICTION
  • Ankara Üniversitesi Adresli: Evet

Özet

Introduction: Behcet's syndrome (BS) is a chronic inflammatory disease with unknown aetiology. Insulin-like growth factor-1 (IGF-1) and IGF-binding protein-3 (IGFBP-3) have important metabolic properties such as anabolic, cytoprotective and anti-inflammatory effects. Circulating IGF-1 and IGF-1/IGFBP-3 concentrations are associated with adiposity and insulin resistance.