Broncholith caused by donor-acquired histoplasmosis in a lung transplant recipient


Shah S. S., Karnak D., Shah S. N., Budev M., Machuzak M., Gildea T. R., ...Daha Fazla

JOURNAL OF HEART AND LUNG TRANSPLANTATION, cilt.26, sa.4, ss.407-410, 2007 (SCI-Expanded) identifier identifier identifier

Özet

A broncholith is a calcified lymph node that erodes into and partially or completely obstructs the bronchial lumen. The natural history of broncholiths is poorly understood. They are frequently encountered.in residents of areas that are endemic for Histoplasma capsulatum and Mycobacterium tuberculum. We report the first case of a broncholith in which the fungus Histoplasma capsulatum was transferred from a donor to a lung transplant (LTx) recipient. Our report highlights the time course of broncholith development and its successful management. We suspect that broncholithiasis and transmission of Histoplasma capsulatum from a donor to the recipient are under-reported in the LTx literature. We hypothesize that histoplasmosis can be transmitted from the donor to the recipient and the duration in the formation of calcification of the lymph node or the broncholith can be anywhere from 2 to 10 months.