Psychotic disorder and Sheehan's syndrome: Etiology or comorbidity?: A case report


Tikir B., Göka E., Aydemir M. Ç., Gürkan Ş.

Turk Psikiyatri Dergisi, cilt.26, sa.2, ss.142-145, 2015 (SSCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 2
  • Basım Tarihi: 2015
  • Dergi Adı: Turk Psikiyatri Dergisi
  • Derginin Tarandığı İndeksler: Social Sciences Citation Index (SSCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.142-145
  • Anahtar Kelimeler: Sheehan's syndrome, postpartum hypopituitarism, psychosis, HYPOPITUITARISM, SCHIZOPHRENIA, PITUITARY
  • Ankara Üniversitesi Adresli: Evet

Özet

Sheehan's Syndrome, also called postpartum hypopituitarism, is a syndrome characterized by heavy bleeding, during or after delivery, and necrosis of the pituitary gland due to hypovolemic shock. Sheehan syndrome presents with agalactorrhea, amenorrhea, hypoythyroidism and hypoglycemia, in addition to psychiatric manifestations, such as psychosis. In this study, we report a case of Sheehan's syndrome that presented with a psychotic disorder. The patient was a 44 year-old, female patient, married. She was admitted for withdrawal, irritability, insomnia, hearing voices telling her to harm herself, do evil to others, and thoughts about that her husband was in an adulterous relationship. She was diagnosed as having a psychotic disorder and treated with olanzapine 20 mg/day. She had hypopituitarism symptoms, thus hormone tests and a cranial MRI were performed. Sheehan's syndrome was diagnosed and prednisolone and thyroxine were added to the treatment. Her symptoms disappeared one months later. Olanzapine was stopped after 4 months and her treatment continued with prednisolone and thyroxine. Studies concerning the etiology of psychotic symptoms refer to endocrine and autoimmune systems. In this study, we discuss a case that in which the diagnosis was a psychotic disorder and Sheehan's Syndrome, diagnosed 24 years later, and the etiological aspect, including the follow-up period and treatment.