Risk factors for valproic acid induced hyperammonemia and its association with cognitive functions

DUMAN B., Can K. C., Agtas-Ertan E., ERDOĞAN S., İLHAN R. S., DOĞAN Ö., ...Daha Fazla

GENERAL HOSPITAL PSYCHIATRY, cilt.59, ss.67-72, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 59
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.genhosppsych.2019.05.005
  • Dergi Adı: GENERAL HOSPITAL PSYCHIATRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Sayfa Sayıları: ss.67-72
  • Anahtar Kelimeler: Hyperammonemia, Valproic acid, Bipolar disorder, Epilepsy, Attention, Memory, ENCEPHALOPATHY
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective: Valproic acid (VPA)-induced hyperammonemia (VIH), is an increase in blood ammonia levels without any alteration of hepatic enzymes, which can occur during VPA treatment. We aimed to determine the prevalence rate and the risk factors for VIH and its association with cognitive functions.