Risk factors for valproic acid induced hyperammonemia and its association with cognitive functions

DUMAN, BERKER; Can, KAZIM; Agtas-Ertan, Ece; ERDOĞAN, SEYDA; İLHAN, RİFAT; DOĞAN, ÖZLEM; KUMBASAR, HAKAN; Camsari, Ulas

doi:10.1016/j.genhosppsych.2019.05.005

Risk factors for valproic acid induced hyperammonemia and its association with cognitive functions

Atıf İçin Kopyala

DUMAN B., Can K. C., Agtas-Ertan E., ERDOĞAN S., İLHAN R. S., DOĞAN Ö., ...Daha Fazla

GENERAL HOSPITAL PSYCHIATRY, cilt.59, ss.67-72, 2019 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 59
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.genhosppsych.2019.05.005
Dergi Adı: GENERAL HOSPITAL PSYCHIATRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
Sayfa Sayıları: ss.67-72
Anahtar Kelimeler: Hyperammonemia, Valproic acid, Bipolar disorder, Epilepsy, Attention, Memory, ENCEPHALOPATHY
Ankara Üniversitesi Adresli: Evet

Özet

Objective: Valproic acid (VPA)-induced hyperammonemia (VIH), is an increase in blood ammonia levels without any alteration of hepatic enzymes, which can occur during VPA treatment. We aimed to determine the prevalence rate and the risk factors for VIH and its association with cognitive functions.