Treatment of autonomous ovarian follicular cyst with long-term anastrozole therapy

Engiz O., BERBEROĞLU M., ŞIKLAR Z., BİLİR P., Ocal G.

INDIAN JOURNAL OF PEDIATRICS, cilt.76, sa.9, ss.950-951, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 76 Sayı: 9
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1007/s12098-009-0190-2
  • Dergi Adı: INDIAN JOURNAL OF PEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.950-951
  • Anahtar Kelimeler: Peripheral precocious puberty, Autonomous ovarian cyst, Anastrozole, McCune Albright syndrome
  • Ankara Üniversitesi Adresli: Evet

Özet

Functional follicular ovarian cysts are frequently reported in girls with peripheral precocious puberty (PP). These cysts are usually self-limiting and resolve spontaneously. Several drugs like antiestrogens (tamoxifen) and new aromatase inhibitors are seldom used for treatment. Here we report a girl with peripheral PP who presented with unilateral enlargement of the ovary and a recurrent autonomous ovarian cyst. No skin pigmentation or bone anomaly was noted. The patient was successfully treated with anastrozole, a highly selective aromatase inhibitor. No adverse reaction was noted. Anastrozole is a safe and tolerable drug especially used to suppress estrogen action.