NUCLEAR MEDICINE COMMUNICATIONS, cilt.21, sa.8, ss.769-773, 2000 (SCI-Expanded)
This study evaluates brain perfusion in long-term inhalant abusers of toluene, acetone, benzene and derivatives. Ten patients in the age range 16-18 years (mean, 17.3 +/- 0.67 years), who had been inhalant dependent for a mean period of 48.3 +/- 6.2 months, but who had stopped using inhalants for 1-11 months (mean, 5.4 +/- 2.1 months), and ten controls (mean age, 17.3 +/- 0.67 years) were included in the study. Psychiatric tests, biochemical tests and Tc-99m-hexamethylpropyleneamine oxime (Tc-99m-HMPAO) brain single photon emission computed tomography (SPECT) were performed on all patients. Brain SPECT images were evaluated qualitatively and quantitatively.